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"Anomalies and Curiosities of Medicine"

The first mention of the yaws disease is by
Oviedo, in 1535, who met with it in San Domingo. Although
Sauvages at the end of the last century was the first to give an
accurate description of this disease, many physicians had
observed it before.
Frambesia or yaws was observed in Brazil as early as 1643, and in
America later by Lebat in 1722. In the last century Winterbottom
and Hume describe yaws in Africa, Hume calling it the African
distemper. In 1769 in an essay on the "Natural History of
Guiana," Bancroft mentions yaws; and Thomson speaks of it in
Jamaica. Hillary in 1759 describes yaws in Barbadoes; and Bajou
in Domingo and Cayenne in 1777, Dazille having already observed
it in San Domingo in 1742.
Crocker takes his account of yaws from Numa Rat of the Leeward
Islands, who divides the case into four stages: incubation,
primary, secondary, and tertiary. The incubation stage is taken
from the date of infection to the first appearance of the local
lesion at the sight of inoculation. It varies from three to ten
weeks. The symptoms are vague, possibly palpitation, vertigo,
edema of the limbs and eyelids. The primary stage begins with the
initial lesion, which consists of a papule which may be found
most anywhere on the body.


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