Most of the cases that have been reported as a
combination of these two diseases are now thought to be only a
syringomyelia. A recent case is reported by Marie. In this
connection it is interesting to notice a case of what might be
called acute symptomatic transitory pseudoacromegaly, reported by
Potovski: In an insane woman, and without ascertainable cause,
there appeared an enlargement of the ankles, wrists, and
shoulders, and later of the muscles, with superficial trophic
disturbances that gradually disappeared. The author excludes
syphilis, tuberculosis, rheumatism, gout, hemophilia, etc., and
considers it to have been a trophic affection of cerebral origin.
Cases of pneumonia osteoarthropathy simulating acromegaly have
been reported by Korn and Murray.
Megalocephaly, or as it was called by Virchow, leontiasis ossea,
is due to a hypertrophic process in the bones of the cranium. The
cases studied by Virchow were diffuse hyperostoses of the
cranium. Starr describes what he supposes to be a case of this
disease, and proposes the title megalocephaly as preferable to
Virchow's term, because the soft parts are also included in the
hypertrophic process. A woman of fifty-two, married but having no
children, and of negative family history, six years before the
time of report showed the first symptoms of the affection, which
began with formication in the finger-tips.
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