Unverricht, Thomas, and Ransom
report cases in which the ocular lesions, indicative of pituitary
trouble, were quite prominent. Of 22 cases collected by Tamburini
19 showed some change in the pituitary body, and in the remaining
three cases either the diagnosis was uncertain or the disease was
of very short duration. Linsmayer reported a case in which there
was a softened adenoma in the pituitary body, and the thymus was
absent.
Hersman reports an interesting case of progressive enlargement of
the hands in a clergyman of fifty. Since youth he had suffered
with pains in the joints. About three years before the time of
report he noticed enlargement of the phalangeal joint of the
third finger of the right hand. A short time later the whole hand
became gradually involved and the skin assumed a darker hue.
Sensation and temperature remained normal in both hands;
acromegaly was excluded on account of the absence of similar
changes elsewhere. Hersman remarks that the change was probably
due to increase in growth of the fibrous elements of the
subcutaneous lesions about the tendons, caused by rheumatic
poison. Figure 283 shows the palmer and dorsal surfaces of both
hands.
Chiromegaly is a term that has been applied by Charcot and
Brissaud to the pseudoacromegaly that sometimes occurs in
syringomyelia.
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