Peters witnessed this idiosyncrasy several
times and believed it to be permanent. The most unpleasant of the
untoward symptoms of quinin exhibition are the disturbances of
the organs of special sense. Photophobia, and even transient
amblyopia, have been observed to follow small doses. In the
examination of cases of the untoward effects of quinin upon the
eye, Knapp of New York found the power of sight diminished in
various degrees, and rarely amaurosis and immobility of the
pupils. According to Lewin, the perceptions of color and light
are always diminished, and although the disorder may last for
some time the prognosis is favorable. The varieties of the
disturbances of the functions of the ear range from tinnitus
aurium to congestion causing complete deafness. The
gastro-intestinal and genito-urinary tracts are especially
disposed to untoward action by quinin. There is a case recorded
in which, after the slightest dose of quinin, tingling and
burning at the meatus urinarius were experienced. According to
Lewin, there is mentioned in the case reported by Gauchet a
symptom quite unique in the literature of quinin, viz.,
hemoptysis. Simon de Ronchard first noted the occurrence of
several cases of hemoptysis following the administration of doses
of eight grains daily.
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