Persons thus
attacked complain, shortly after the injection, of an intensely
sour or bitter taste, which for the most part ceases after
elimination of the morphin. Von Graefe and Sommerfrodt speak of a
spasm of accommodation occurring after ingestion of medicinal
doses of morphin. There are several cases on record in which
death has been produced in an adult by the use of 1/2 to 1/6
grain of morphin. According to Wood, the maximum doses from which
recovery has occurred without emesis are 55 grains of solid
opium, and six ounces of laudanum. According to the same
authority, in 1854 there was a case in which a babe one day old
was killed by one minim of laudanum, and in another case a few
drops of paregoric proved fatal to a child of nine months.
Doubtful instances of death from opium are given, one in an adult
female after 30 grains of Dover's powder given in divided doses,
and another after a dose of 1/4 grain of morphin. Yavorski cites
a rather remarkable instance of morphin-poisoning with recovery:
a female took 30 grains of acetate of morphin, and as it did not
act quickly enough she took an additional dose of 1/2 ounce of
laudanum. After this she slept a few hours, and awoke complaining
of being ill.
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