The dermal
manifestations, such as urticaria and eruptions resembling the
exanthem of scarlatina, are too well known to need mention here.
An enema containing 80 grains of belladonna root has been
followed in five hours by death, and Taylor has mentioned
recovery after the ingestion of three drams of belladonna. In
1864 Chambers reported to the Lancet the recovery of a child of
four years who took a solution containing 1/2 grain of the
alkaloid. In some cases the idiosyncrasy to belladonna is so
marked that violent symptoms follow the application of the
ordinary belladonna plaster. Maddox describes a ease of poisoning
in a music teacher by the belladonna plaster of a reputable
maker. She had obscure eye-symptoms, and her color-sensations
were abnormal. Locomotor equilibration was also affected. Golden
mentions two cases in which the application of belladonna
ointment to the breasts caused suppression of the secretion of
milk. Goodwin relates the history of a case in which an infant
was poisoned by a belladonna plaster applied to its mother's
breast and died within twenty-four hours after the first
application of the plaster. In 1881 Betancourt spoke of an
instance of inherited susceptibility to belladonna, in which the
external application of the ointment produced all the symptoms of
belladonna poisoning.
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